Colorectal Cancer Alliance is the largest and oldest colorectal cancer non-profit organization in the US.

The Colorectal Cancer Alliance offers a variety of patient support services including grant programs, monthly webinars, a helpline, chat forum and a Buddy Program, which provides both survivors and caregivers with a chance to connect with someone who has gone through a similar experience. The organization serves as a source of information about colorectal health. The Colorectal Cancer Alliance also distributes colorectal cancer awareness merchandise and printed materials.